Real World Evidence & Late Phase Systematic Literature Review and Meta-Analysis

Systematic Literature Review and Meta-Analysis

Systematic review and meta-analyses use transparent, structured and reproducible methodologies to critically analyze published studies to answer your specific research question.

At CTI, all systematic reviews are performed by experienced scientists, researchers and statisticians (MD, PhD, PharmD, RN). We utilize methods derived from the emerging science of literature review and statistical synthesis of clinical evidence, in compliance with guidelines from MOOSE and PRISMA.

To ensure comprehensive capture of all published studies, the CTI process employs:


Two Independent reviewers
  • Search, screen, and extract data from accepted studies 
  • Differences are resolved via consensus conference to ensure the accuracy and completeness of the dataset  

Advanced Meta-analytic techniques include: 


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